Centre for Vocational Studies
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    Dr. Rais Ahmad Ganai

    Assistant Professor
    rais.ganai@iust.ac.in
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Faculty Member
S.No.PublicationWebLink
1 LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. Gary LeRoy, Ozgur Oksuz, Nicolas Descostes, Yuki Aoi, Rais A Ganai, Havva Ortabozkoyun Kara, Jia-Ray Yu, Chul-Hwan Lee, James Stafford, Ali Shilatifard, Danny Reinberg. Science Advances. 5 (10), eaay3068-- -- ( 01-08-2019 ) 
2 Distinct stimulatory mechanisms regulate the catalytic activity of polycomb repressive complex 2. Chul-Hwan Lee, Marlene Holder, Daniel Grau, Ricardo Saldaña-Meyer, Jia-Ray Yu, Rais Ahmad Ganai, Jenny Zhang, Miao Wang, Gary LeRoy, Marc-Werner Dobenecker, Danny Reinberg, Karim-Jean Armache. Molecular cell. 70 (3), 435-448 (2018)-- -- ( 01-03-2018 ) 
3 Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli. N. S. Singh, Rais Ahmad, R Sangeetha and Varshney U. Journal of Molecular Biology. 380, 451-464 (2008)-- -- ( 01-04-2008 ) 
4 Yeast DNA polymerase epsilon catalytic core and holoenzyme have comparable catalytic rates. Rais A. Ganai, Pia Osterman and Erik Johansson. Journal of Biological Chemistry. 290:3825-3855 (2015)-- -- ( 01-02-2015 ) 
5 Strand displacement synthesis properties of DNA polymerase epsilon. Rais A. Ganai, Xiao-Ping Zhang, Wolf-Dietrich Heyer and Erik Johansson. Nucleic Acids Research. 44:8229-40 (2016).-- -- ( 01-07-2016 ) 
6 Switching between polymerase and exonuclease sites in DNA polymerase epsilon. Rais A. Ganai, Göran Bylund and Erik Johansson. Nucleic Acids Research. 43:932-942 (2015).-- -- ( 01-03-2015 ) 
7 Structural basis for processive polymerization by yeast DNA polymerase epsilon Matthew Hogg, Pia Osterman, Göran Bylund, Rais A. Ganai, Else-Britt Lundstrom, Elisabeth Sauer-Ericksson and Erik Johansson Nature Structural and Molecular Biology, 21, 49–55 (2014).-- -- ( 04-06-2014 ) 
8 DNA Replication – A Matter of Fidelity. Rais A. Ganai and Erik Johansson. Molecular Cell. 62: 745–755 (2016).-- -- ( 01-05-2016 ) 
S.No.Project TitleProject StatusFunding AgencyPI COPI InvestgatorAmount of GrantDuration
1 To investigate the catalytic and non-catalytic roles of replicative DNA polymerases in preserving replication fork integrity during replication stressOngoingSERB-DSTPrincipal Investigator55.003 Years
2 To investigate the mechanistic basis of anomalous Polycomb inhibition in prostate cancersOngoingICMRPrincipal Investigator45.003 Years
3 Dynamic Polycomb interactome and its role in development and diseaseCompletedSERBPrincipal Investigator1185 Years
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