Watson-Crick Centre for Molecular Medicine
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    Dr. Arsheed Ahmad Ganaie

    Assistant Professor
    arsheed.ganaie@gmail.com
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Faculty Member
S.No.PublicationWebLink
1 Ganaie AA, Hussain T, Ferrari M, et al., …M Saleem. (2021) Identifying novel genetic mechanism underlying ADT resistance in African American patients.-- -- ( 25-12-2021 ) 
2 Ganaie AA, Maqbool R, Beigh FA, Umbreen S, Dulyaninova N G, Konety B R and Saleem M. Developing novel inhibitors of S100A4 for neuroendocrine (NE) and metastatic prostate cancer: systematic testing using relevant models and drug development techniques (Accepted in Cancer research)-- -- ( 25-12-2021 ) 
3 Differential thermal stability, conformational stability and unfolding behavior of Eis proteins from Mycobacterium smegmatis and Mycobacterium tuberculosis. Anand S, Ganaie AA, Sharma C. PLoS One. 2019 Mar 25;14(3):e0213933. doi: 10.1371/journal.pone.0213933. eCollection 2019. PMID: 30908529-- -- ( 25-12-2021 ) 
4 Thermostable hexameric form of Eis (Rv2416c) protein of M. tuberculosis plays an important role for enhanced intracellular survival within macrophages. Ganaie AA, Lella RK, Solanki R, Sharma C. PLoS One. 2011;6(11):e27590. doi: 10.1371/journal.pone.0027590. Epub 2011 Nov 16. PMID: 22110681 -- -- ( 25-12-2021 ) 
5 Interaction of Erp Protein of Mycobacterium tuberculosis with Rv2212 Enhances Intracellular Survival of Mycobacterium smegmatis. Ganaie AA, Trivedi G, Kaur A, Jha SS, Anand S, Rana V, Singh A, Kumar S, Sharma C. J Bacteriol. 2016 Sep 22;198(20):2841-52. doi: 10.1128/JB.00120-16. Print 2016 Oct 15. PMID: 27481930 -- -- ( 25-12-2021 ) 
6 Identifying and treating ROBO1-ve /DOCK1+ve prostate cancer: An aggressive cancer subtype prevalent in African American patients. Ferrari MG, Ganaie AA, Shabenah A, Mansini AP, Wang L, Murugan P, Davicioni E, Wang J, Deng Y, Hoeppner LH, Warlick CA, Konety BR, Saleem M. Prostate. 2020 Sep;80(13):1045-1057. doi: 10.1002/pros.24018. Epub 2020 Jul 20. PMID: 32687658 -- -- ( 25-12-2021 ) 
7 A novel terpenoid class for prevention and treatment of KRAS-driven cancers: Comprehensive analysis using in situ, in vitro, and in vivo model systems. Ganaie AA, Siddique HR, Sheikh IA, Parray A, Wang L, Panyam J, Villalta PW, Deng Y, Konety BR, Saleem M. Mol Carcinog. 2020 Aug;59(8):886-896. doi: 10.1002/mc.23200. Epub 2020 Apr 15. PMID: 32291806 -- -- ( 25-12-2021 ) 
8 COMMD3:BMI1 Fusion and COMMD3 Protein Regulate C-MYC Transcription: Novel Therapeutic Target for Metastatic Prostate Cancer. Umbreen S, Banday MM, Jamroze A, Mansini AP, Ganaie AA, Ferrari MG, Maqbool R, Beigh FH, Murugan P, Morrissey C, Corey E, Konety BR, Saleem M. Mol Cancer Ther. 2019 Nov;18(11):2111-2123. doi: 10.1158/1535-7163.MCT-19-0150. Epub 2019 Aug 29. PMID: 31467179 -- -- ( 25-12-2021 ) 
9 Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression. Ganaie AA, Parray A, Hussain T, Shabaneh A, Jamroze A, Ferrari MG, Wang L, Liao DJ, Koochekpour S, Nanda S, Wang J, Deng Y, Gradilone SA, Hinchcliffe EH, Konety BR, Saleem M. Transl Oncol. 2019 Aug;12(8):1056-1071. doi: 10.1016/j.tranon.2019.05.002. Epub 2019 Jun 4. PMID: 31174057 -- -- ( 25-12-2021 ) 
10 Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor. Ganaie AA, Mansini AP, Hussain T, Rao A, Siddique HR, Shabaneh A, Ferrari MG, Murugan P, Klingelhöfer J, Wang J, Ambartsumian N, Warlick CA, Konety BR, Saleem M. Mol Cancer Ther. 2020 Dec;19(12):2598-2611. doi: 10.1158/1535-7163.MCT-20-0410. Epub 2020 Sep 30. PMID: 32999046 -- -- ( 25-12-2021 ) 
11 BMI1 Drives Metastasis of Prostate Cancer in Caucasian and African-American Men and Is A Potential Therapeutic Target: Hypothesis Tested in Race-specific Models. Ganaie AA, Beigh FH, Astone M, Ferrari MG, Maqbool R, Umbreen S, Parray AS, Siddique HR, Hussain T, Murugan P, Morrissey C, Koochekpour S, Deng Y, Konety BR, Hoeppner LH, Saleem M. Clin Cancer Res. 2018 Dec 15;24(24):6421-6432. doi: 10.1158/1078-0432.CCR-18-1394. Epub 2018 Aug 7. PMID: 30087142 -- -- ( 25-12-2021 ) 
S.No.Project TitleProject StatusFunding AgencyPI COPI InvestgatorAmount of GrantDuration
1 To investigate the role of MDM2 as a Master Regulator and Therapeutic Target in Neuroendocrine Prostate CancerOngoingDBTPrincipal Investigator113.605 years
2 To Study the Novel Role of Cullin- 3 SPOP E3 Ligase mediated immune surveillance in Prostate Cancer by promoting the degradation of Next generation immune checkpoint inhibitor CD73OngoingSERB-DSTPrincipal Investigator50.343 years
No recors(s) found
S.No.InventorsTitlePatentNoPublisher
1 Arsheed Ganaie and Mohammad Saleem“Targeting Neuroendocrine Prostate Cancer with small molecule inhibitors”Patent File 0110.000654US60United States PTO